교수 프로필
- Major생명자원소재공학
- Tel063-850-0847
- Fax063-850-0834
- Emailejyun@jbnu.ac.kr
- Lab제2환생대관 406호
- Homepagehttps://sites.google.com/view/bioactive-materials-lab/home
주요 학력
- 2015.02. 고려대학교 생명공학과 졸업 (석박사통합)
- 2008.02. 중앙대학교 생명공학과 졸업 (학사)
주요 경력
- 2022.03. ~ 현재 : 전북대학교 생명공학부 조교수
- 2016.07. ~ 2022.02. : 고려대학교 식품생의학안전연구소 연구교수
- 2016.08. ~ 2018.08. : University of Illinois Urbana-Champaign 박사 후 연구원
- 2015.07. ~ 2016.06. : 고려대학교 BK21Plus BT사업단 연구교수
- 2013.09. ~ 2014.03. : University of Illinois Urbana-Champaign 방문연구원
경력 활동
- 한국미생물생명공학회 회원
- 한국대사체학회 회원
- 한국식품과학회 회원
주요 수상 경력
- 2021. 06. 한국미생물생명공학회, International Symposium 강연 감사장
- 2019. 06. 한국식품과학회, 신진과학자강연 감사패
- 2019. 06. 한국미생물생명공학회, 신진과학자강연 감사패
- 2016. 05. BK21Plus 생명공학원사업단, 최우수연구자상
- 2015. 06. 한국미생물생명공학회, 신진과학자강연 감사패
- 2015. 02. 고려대학교 대학원, 우수논문상
- 2015. 04. 한국대사체학회, 우수발표상
- 2014. 04. 한국대사체학회, 우수발표상
- 2012. 09. International Biotechnology Symposium and Exhibition, Biotechnology and Bioengineering Best Poster Award
- 2009. 06. 한국미생물생명공학회, 우수포스터발표상
관심 연구 분야
- Bio-based Products
- Microbiome
- Synthetic Biology
- Metabolic Engineering
- Metabolomics
수행 연구
- Discovery of the metabolic interactions between human gut bacteria conferring health benefits to the host
- Production of new bioactive materials using the engineered microbial platform
- Adaptive laboratory evolution of probiotics to reveal key genetic factors improving substrate utilization
Publications in Peer-reviewed Journals
Selected Publications
1. Eun Ju Yun ‡, Yoonho Cho (co-first author)‡, Na Ree Han, In Jung Kim, Hyoung Min Han, Yong-Su Jin, and Kyoung Heon Kim* (2021) Increased production of colanic acid by an engineered Escherichia coli strain, mediated by genetic and environmental perturbations. to be submitted to Applied Biochemistry and Biotechnology (IF= 2.926) 193 (12), 4083-4096
2. Eun Ju Yun, Seung-Oh Seo, Suryang Kwak, Eun Joong Oh, Sun Hee Lee, Yong-Su Jin*, Kyoung Heon Kim* (2021) Fast filtration with a vacuum manifold system as a rapid and robust metabolome sampling method for Saccharomyces cerevisiae. Process Biochemistry (IF= 3.757) 110, 195-200.
3. Eun Ju Yun, Sora Yu, Na Jung Park, Yoonho Cho, Na Ree Han, Yong-Su Jin*, Kyoung Heon Kim* (2021) Metabolic and enzymatic elucidation of cooperative degradation of red seaweed agarose by two human gut bacteria. Scientific Reports (IF= 4.379) 11 (1), 13955.
4. Eun Ju Yun‡, Guo-Chang Zhang‡, Christine Atkinson‡, Stephan Lane, Jing-Jing Liu, Don Ort, Youg-Su Jin* (2021) Glycolate production by a Chlamydomonas reinhardtii mutant lacking carbon-concentrating mechanism. Journal of Biotechnology (IF= 3.307) 335 (20), 39-46.
5. Eun Ju Yun‡, Sora Yu‡, Young-Ah Kim, Jing-Jing Liu, Nam Joo Kang, Yong-Su Jin*, Kyoung Heon Kim* (2021) In vitro prebiotic and anti-colon cancer activities of agar-derived sugars from red seaweeds. Marine Drugs (IF= 5.118) 19 (4), 213
6. Na Jung Park‡, Sora Yu‡, Dong Hyun Kim, Eun Ju Yun (co-corresponding author)*, Kyoung Heon Kim* (2021) Characterization of BpGH16A of Bacteroides plebeius, a key enzyme initiating the depolymerization of agarose in the human gut. Applied Microbiology and Biotechnology (IF= 4.813) 105 (2), 617-625
7. Sora Yu‡, Eun Ju Yun (co-first author)‡, Dong Hyun Kim, So Young Park, Kyoung Heon Kim* (2020) Dual agarolytic pathways in a marine bacterium, Vibrio sp. Strain EJY3: Molecular and enzymatic verification. Applied and Environmental Microbiology (IF= 4.792) 86 (6), e02724-19
8. Sora Yu‡, Eun Ju Yun (co-first author)‡, Dong Hyun Kim, So Young Park, Kyoung Heon Kim* (2019) Anticariogenic activity of agarobiose and agarooligosaccharides derived from red macroalgae. Journal of Agricultural and Food Chemistry (IF= 5.279) 67 (26), 7297-7303
9. Eun Ju Yun, Jing-Jing Liu, Jaewon Lee, Suryang Kwak, Sora Yu, Kyoung Heon Kim*, Yong-Su Jin* (2019) Biosynthetic routes for producing various fucosyl-oligosaccharides. ACS Synthetic Biology (IF= 5.110) 8 (2), 415-424
10. Eun Ju Yun, Eun Joong Oh, Jing-Jing Liu, Sora Yu, Dong Hyun Kim, Suryang Kwak, Kyong Heon Kim*, Yong-Su Jin* (2018) Promiscuous activities of heterologous enzymes lead to unintended metabolic rerouting in Saccharomyces cerevisiae engineered to assimilate various sugars from renewable biomass. Biotechnology for Biofuels (IF= 6.040) 11 (1), 140
11. Eun Ju Yun‡, James Lee‡, Do Hyoung Kim, Jungyeon Kim, Sooah Kim, Yong-Su Jin, Kyoung Heon Kim* (2018) Metabolomic elucidation of the effects of media and carbon sources on fatty acid production by Yarrowia lipolytica. Journal of Biotechnology (IF= 3.307) 272-273 (20), 7-13
12. Eun Ju Yun, Sora Yu, Sooah Kim, Kyoung Heon Kim* (2018) Metabolomic response of a marine bacterium to 3,6-anhydro-l-galactose, the rare sugar from red macroalgae, as the sole carbon source. Journal of Biotechnology (IF= 3.307) 270 (20), 12-20
13. Sora Yu, In-Geol Choi, Eun Ju Yun (co-corresponding author)*, Kyoung Heon Kim* (2018) High substrate specificity of 3,6-anhydro-l-galactose dehydrogenase indicates its essentiality in the agar catabolism of a marine bacterium. Process Biochemistry (IF= 3.757) 64, 130-135
14. Ji Hye Kim‡, Eun Ju Yun (co-first author)‡, Sora Yu, Kyoung Heon Kim*, Nam Joo Kang* (2017) Different levels of skin whitening activity among 3,6-anhydro-l-galactose, agarooligosaccharides, and neoagarooligosaccharides. Marine Drugs (IF= 5.118) 15 (10), 321
15. Eun Ju Yun, Sora Yu, Kyoung Heon Kim* (2017) Current knowledge on agarolytic enzymes and the industrial potential of agar-derived sugars. Applied Microbiology and Biotechnology (IF= 4.813) 101 (14), 5581-5589
16. Eun Ju Yun, Ah Reum Lee, Jung Hyun Kim, Kyung Mun Cho, Kyoung Heon Kim* (2017) 3,6-Anhydro-l-galactose, a rare sugar from agar, a new anticariogenic sugar to replace xylitol. Food Chemistry (IF= 7.514) 221(15), 976-983
17. Eun Ju Yun, Sun Hee Lee, Sooah Kim, Sae Hun Kim, Kyoung Heon Kim* (2017) Global profiling of metabolic response of Caenorhabditis elegans against Escherichia coli O157:H7. Process Biochemistry (IF= 3.757) 53, 36-43
18. Jung Hyun Kim‡, Eun Ju Yun (co-first author)‡, Nari Seo, Sora Yu, Dong Hyun Kim, Kyung Mun Cho, Hyun Joo An, Jae-Han Kim, In-Geol Choi, Kyoung Heon Kim* (2017) Enzymatic liquefaction of agarose above the sol−gel transition temperature using a thermostable endo-type β-agarase, Aga16B. Applied Microbiology and Biotechnology (IF= 4.813) 101 (3), 1111-1120
19. Eun Ju Yun, Hee Taek Kim, Kyung Mun Cho, Sora Yu, Sooah Kim, In-Geol Choi, Kyoung Heon Kim* (2016) Pretreatment and saccharification of red macroalgae to produce fermentable sugars. Bioresource Technology (IF= 9.642) 199, 311-318
20. Chan Hyoung Lee‡, Eun Ju Yun (co-first author)‡, Hee Taek Kim, In-Geol Choi, Kyoung Heon Kim* (2015) Saccharification of agar using hydrothermal pretreatment and enzymes supplemented with agarolytic β-galactosidase. Process Biochemistry (IF= 3.757) 50 (10), 1629-1633
21. Eun Ju Yun, Suryang Kwak, Soo Rin Kim, Yong-Cheol Park, Yong-Su Jin*, Kyoung Heon Kim* (2015) Production of (S)-3-hydroxyburate by metabolically engineered Saccharomyces cerevisiae. Journal of Biotechnology (IF= 3.307) 10(209), 23-30
22. Eun Ju Yun, In-Geol Choi, Kyoung Heon Kim* (2015) Red macroalgae as a sustainable resource for bio-based products. Trends in Biotechnology (IF= 19.536) 33 (5), 247-249
23. Eun Ju Yun, Saeyoung Lee, Hee Taek Kim, Jeffrey G Pelton, Sooah Kim, Hyeok‐Jin Ko, In‐Geol Choi*, Kyoung Heon Kim* (2015) The novel catabolic pathway of 3,6-anhydro-L-galactose, the main component of red macroalgae, in a marine bacterium. Environmental Microbiology (IF= 5.491) 17 (5), 1677-1688
24. Eun Ju Yun, Saeyoung Lee, Ji Hye Kim, Bo Bae Kim, Hee Taek Kim, Sun Hee Lee, Jeffrey G Pelton, Nam Joo Kang*, In-Geol Choi*, Kyoung Heon Kim* (2013) Enzymatic production of 3,6-anhydro-l-galactose from agarose and its purification and in vitro skin whitening and anti-inflammatory activities. Applied Microbiology and Biotechnology (IF= 4.813) 97 (7), 2961-2970
25. Hanseong Roh‡, Eun Ju Yun (co-first author)‡, Saeyoung Lee, Hyeok-Jin Ko, Sujin Kim, Byung-Yong Kim, Heesang Song, Kwang-il Lim, Kyoung Heon Kim, In-Geol Choi* (2012) Genome sequence of Vibrio sp. Strain EJY3, an agarolytic marine bacterium metabolizing 3,6-anhydro-l-galactose as a sole carbon source. Journal of Bacteriology (IF= 3.490) 194 (10), 2773-2774
26. Eun Ju Yun, Min Hye Shin, Jeong-Jun Yoon, Yong Jin Kim, In-Geol Choi, Kyoung Heon Kim* (2011) Production of 3,6-anhydro-l-galactose from agarose by agarolytic enzymes of Saccharophagus degradans 2-40. Process Biochemistry (IF= 3.757) 46 (1), 88-93
Other Publications
1. Sujit Sadashiv Jagtap, Anshu Deewan, Jing-Jing Liu, Hanna E Walukiewicz, Eun Ju Yun, Yong-Su Jin, Christopher V Rao* (2021) Integrating transcriptomic and metabolomic analysis of the oleaginous yeast Rhodosporidium toruloides IFO0880 during growth under different carbon sources. Applied Microbiology and Biotechnology (IF= 4.813) 105 (19), 7411-7425
2. Jae Won Lee, Suryang Kwak, Jing-Jing Liu, Eun Ju Yun, Yong-Su Jin* (2021) 2’-Fucosyllactose production in engineered Escherichia coli with deletion of waaF and wcaJ and overexpression of FucT2. Journal of Biotechnology (IF= 3.307) 340, 30-38.
3. Jing-Jing Liu‡, William Woodruff‡, Anshu Deewan‡, Sujit Sadashiv Jagtap, Eun Ju Yun, Hanna E. Walukiewicz, Yong-Su Jin*, Christopher Rao* (2021) Investigating the role of the transcriptional regulator Ure2 on the metabolism of Saccharomyces cerevisiae: a multi-omics approach. Applied Microbiology and Biotechnology (IF= 4.813) 105, 5103–5112.
4. Yerin Jin‡, Sora Yu‡, Jing-Jing Liu, Eun Ju Yun, Jae Won Lee, Youg-Su Jin*, Kyoung Heon Kim* (2021) Probiotic yeast Saccharomyces boulardii as a microbial cell factory for producing neoagarooligosaccharides, constructed using CRISPR-Cas9. Microbial Cell Factories (IF= 5.328) 20 (1), 1-10.
5. Yerin Jin‡, Sora Yu‡, Dong Hyun Kim, Eun Ju Yun, and Kyoung Heon Kim* (2021) Characterization of neoagarooligosaccharide hydrolase BpGH117 from a human gut bacterium Bacteroides plebeius. Marine Drugs (IF= 5.118) 19 (5), 271.
6. Hyeong Min Han‡, In Jung Kim‡, Eun Ju Yun, Jae Won Lee, Yoonho Cho, Yong-Su Jin, Kyoung Heon Kim* (2021) Overproduction of exopolysaccharide colanic acid by Escherichia coli by strain engineering and media optimization. Applied Biochemistry and Biotechnology (IF= 2.926) 193 (1), 111-127
7. Jae Won Lee, Suryang Kwak, Jing-Jing Liu, Sora Yu, Eun Ju Yun, Dong Hyun Kim, Cassie Liu, Kyoung Heon Kim, Yong-Su Jin* (2020) Enhanced 2′-Fucosyllactose production by engineered Saccharomyces cerevisiae using xylose as a co-substrate. Metabolic Engineering (IF= 9.783) 62, 322-329
8. Dong Hyun Kim, Jing-Jing Liu, Jae Won Lee, Jeffrey G Pelton, Eun Ju Yun, Sora Yu, Yong-Su Jin*, Kyoung Heon Kim* (2020) Biological upgrading of 3,6-anhydro-L-galactose from agarose to a new platform chemical. Green Chemistry (IF= 10.182) 22 (5), 1776-1785
9. Stephan Lane, Yanfei Zhang, Eun Ju Yun, Leah Ziolkowski, Guo-Chang Zhang, José L. Avalos, Yong-Su Jin* (2020) Xylose assimilation enhances production of isobutanol in engineered yeast. Biotechnology and Bioengineering (IF= 4.530) 117, 372-381
10. Hee Taek Kim, Jae Kyun Kim, Hyun Gil Cha, Myung Jong Kang, Hyun Sook Lee, Tae Uk Khang, Eun Ju Yun, Dae-Hee Lee, Bong Keun Song, Si Jae Park, Jeong Chan Joo, Kyoung Heon Kim (2019) Biological valorization of polyethylene terephthalate monomers for waste PET upcycling. ACS Sustainable Chemistry & Engineering (IF= 8.198) 7 (24), 19396-19406
11. Suryang Kwak, Eun Ju Yun, Stephan Lane, Eun Joong Oh, Kyoung Heon Kim, Yong-Su Jin* (2019) Redirection of the glycolytic flux to enhance isoprenoid production in Saccharomyces cerevisiae. Biotechnology Journal (IF= 4.677) 15, 1900173
12. Jing-Jing Liu, Guo-Chang Zhang, Suryang Kwak, Eun Joong Oh, Eun Ju Yun, Kulika Chomvong, Jamie HD Cate, Yong-Su Jin* (2019) Overcoming the thermodynamic equilibrium of an isomerization reaction through oxidoreductive reactions for biotransformation. Nature Communications (IF=14.919) 10 (1), 1356
13. Jing‐Jing Liu, Jae Won Lee, Eun Ju Yun, Sang‐Min Jung, Jin‐Ho Seo, Yong‐Su Jin* (2019) L‐Fucose production by engineered Escherichia coli. Biotechnology and Bioengineering (IF= 4.530) 116 (4), 904-911
14. Suryang Kwak, Jung Hyun Jo, Eun Ju Yun, Yong-Su Jin*, Jin-Ho Seo* (2019) Production of biofuels and chemicals from xylose using native and engineered yeast strains. Biotechnology Advances (IF= 14.227) 37 (2), 271-283
15. Dong Hyun Kim, Eun Ju Yun, Sang-Hyun Lee, Kyoung Heon Kim* (2018) Novel two-step process utilizing a single enzyme for the production of high-titer 3,6-anhydro-l-galactose from agarose derived from red macroalgae. Journal of Agricultural and Food Chemistry (IF= 5.279) 66 (46), 12249-12256
16. Jing-Jing Liu, Suryang Kwak, Panchalee Pathanibul, Jaewon Lee, Sora Yu, Eun Ju Yun, Hayoon Lim, Kyoung Heon Kim, Yong-Su Jin* (2018) Biosynthesis of a functional human milk oligosaccharide, 2′-fucosyllactose, and l-fucose, using engineered Saccharomyces cerevisiae. ACS Synthetic Biology (IF= 5.110) 7 (11), 2529-2536
17. Lahiru N Jayakody, Jing-Jing Liu, Eun Ju Yun, Timothy L. Turner, Eun Joong Oh, Yong-Su Jin* (2018) Direct conversion of cellulose into ethanol and ethyl-β-D-glucoside via engineered Saccharomyces cerevisiae. Biotechnology and Bioengineering (IF= 4.530) 115 (12), 2859-2868
18. Lahiru N Jayakody, Timothy L. Turner, Eun Ju Yun, In Iok Kong, Jing-Jing Liu, Yong-Su Jin* (2018) Expression of Gre2p improves tolerance of engineered xylose-fermenting Saccharomyces cerevisiae to glycolaldehyde under xylose metabolism. Applied Microbiology and Biotechnology (IF= 4.813) 102 (18), 8121-8133
19. Do Hyoung Kim, In Jung Kim, Eun Ju Yun, Yong-Su Jin*, Kyoung Heon Kim* (2018) Metabolic engineering of Saccharomyces cerevisiae by using the CRISPR-Cas9 system for enhanced fatty acid production. Process Biochemistry (IF= 3.757) 73, 23-28
20. Sora Yu, Jing-Jing Liu, Eun Ju Yun, Suryang Kwak, Kyoung Heon Kim*, Yong-Su Jin* (2018) Production of a human milk oligosaccharide 2'-fucosyllactose by metabolically engineered Saccharomyces cerevisiae. Microbial Cell Factories (IF= 5.328) 17, 101
21. Jing-Jing Liu, Guo-Chang Zhang, In Iok Kong, Eun Ju Yun, Jia-Qi Zheng, Dae-Hyuk Kweon, Yong-Su Jin* (2018) A mutation in PGM2 causing inefficient galactose metabolism by the probiotic yeast Saccharomyces boulardii. Applied and Environmental Microbiology (IF= 4.792) 84 (10), e02858-17
22. Saeyoung Lee, Eun Ju Yun, Kyoung Heon Kim, Hye-Yeon Kim, In-Geol Choi* (2017) 3,6-Anhydro-l-galactonate cycloisomerase from Vibrio sp. strain EJY3: crystallization and X-ray crystallographic analysis. Acta Crystallographica Section F Structural Biology Communications (IF= 1.056) F73, 511-514
23. Hee Jin Lee, In Jung Kim, Hak Jin Youn, Eun Ju Yun, In-Geol Choi, Kyoung Heon Kim* (2017) Cellotriose-hydrolyzing activity conferred by truncating the carbohydrate-binding modules of Cel5 from Hahella chejuensis. Bioprocess and Biosystems Engineering (IF= 3.210) 40 (2), 241-249
24. Damao Wang, Do Hyoung Kim, Eun Ju Yun, Yong-Cheol Park, Jin-Ho Seo, Kyoung Heon Kim* (2017) The first bacterial β-1,6-endoglucanase from Saccharophagus degradans 2-40T for the hydrolysis of pustulan and laminarin. Applied Microbiology and Biotechnology (IF= 4.813) 101 (1), 197-204
25. Sang-Hyun Lee, Eun Ju Yun, Jungyeon Kim, Sang Jun Lee, Youngsoon Um, Kyoung Heon Kim* (2016) Biomass, strain engineering, and fermentation processes for butanol production by solventogenic clostridia. Applied Microbiology and Biotechnology (IF= 4.813) 100 (19), 8255-8271
26. Do Hyoung Kim, Damao Wang, Eun Ju Yun, Sooah Kim, Soo Rin Kim*, Kyoung Heon Kim* (2016) Validation of the metabolic pathway of the alginate-derived monomer in Saccharophagus degradans 2-40T by gas chromatography−mass spectrometry. Process Biochemistry (IF= 3.757) 51 (10), 1374-1379
27. Damao Wang, Do Hyoung Kim, Nari Seo, Eun Ju Yun, Hyun Joo An, Jae-Han Kim, Kyoung Heon Kim* (2016) A novel glycoside hydrolase family 5 β-1,3-1,6-endoglucanase from Saccharophagus degradans 2-40T and its transglycosylase activity. Applied and Environmental Microbiology (IF= 4.792) 82 (14), 4340-4349
28. Damao Wang, Eun Ju Yun, Sooah Kim, Do Hyoung Kim, Nari Seo, Hyun Joo An, Jae-Han Kim, Nam Yong Cheong, Kyoung Heon Kim* (2016) Efficacy of acidic pretreatment for the saccharification and fermentation of alginate from brown macroalgae. Bioprocess and Biosystems Engineering (IF= 3.210) 39 (16), 959-966
29. Haiqing Xu, Sooah Kim, Hagit Sorek, Youngsuk Lee, Deokyeol Jeong, Jungyeon Kim, Eun Joong Oh, Eun Ju Yun, David E Wemmer, Kyoung Heon Kim, Soo Rin Kim*, Yong-Su Jin* (2016) PHO13 deletion-induced transcriptional activation prevents sedoheptulose accumulation during xylose metabolism in engineered Saccharomyces cerevisiae. Metabolic Engineering (IF= 9.783) 34, 88-96
30. Sooah Kim, Jungyeon Kim, Eun Ju Yun, Kyoung Heon Kim* (2016) Food metabolomics: from farm to human. Current Opinion in Biotechnology (IF= 9.740) 37, 16-23
31. Thirumalaisamy Babu, Eun Ju Yun, Sooah Kim, Do Hyoung Kim, Kwang Hyeon Liu, Soo Rin Kim*, Kyoung Heon Kim* (2015) Engineering Escherichia coli for the production of adipic acid through the reversed β-oxidation pathway. Process Biochemistry (IF= 3.757) 50 (12), 2066-2071
32. In Jung Kim, Ki Hyun Nam, Eun Ju Yun, Sooah Kim, Hak Jin Youn, Hee Jin Lee, In-Geol Choi, Kyoung Heon Kim* (2015) Optimization of synergism of a recombinant auxiliary activity 9 from Chaetomium globosum with cellulase in cellulose hydrolysis. Applied Microbiology and Biotechnology (IF= 4.813) 99 (20), 8537-8547
33. Chan Hyoung Lee‡, Hee Taek Kim‡, Eun Ju Yun, Ah Reum Lee, Sa Rang Kim, Jae-Han Kim, In-Geol Choi, Kyoung Heon Kim* (2014) A novel agarolytic β-galactosidase acts on agarooligosaccharides for complete hydrolysis of agarose into monomers. Applied and Environmental Microbiology (IF= 4.792) 80 (19), 5965-5973
34. Hee-jin Jun, Ji Hae Lee, Jiyoung Kim, Yaoyao Jia, Kyoung Heon Kim, Kwang Yeon Hwang, Eun Ju Yun, Kyoung-Rok Do, Sung-Joon Lee* (2014) Linalool is a PPARα ligand that reduces plasma TG levels and rewires the hepatic transcriptome and plasma metabolome. Journal of Lipid Research (IF= 5.922) 55 (6), 1098-1110
35. Damao Wang, Hee Taek Kim, Eun Ju Yun, Do Hyoung Kim, Yong-Cheol Park, Hee Chul Woo, Kyoung Heon Kim* (2014) Optimal production of 4-deoxy-L-erythro-5-hexoseulose uronic acid from alginate for brown algae saccharification by combining endo- and exo-type alginate lyases. Bioprocess and Biosystems Engineering (IF= 3.210) 37 (10), 2105-2111
36. Hee Taek Kim, Eun Ju Yun, Damao Wang, Jae Hyuk Chung, In-Geol Choi, Kyoung Heon Kim* (2013) High temperature and low acid pretreatment and agarase treatment of agarose for the production of sugar and ethanol from red seaweed biomass. Bioresource Technology (IF= 9.642) 136, 582-587
37. Sooah Kim, Eun Ju Yun, Md Aktar Hossain, Hojoung Lee, Kyoung Heon Kim* (2012). Global profiling of ultraviolet-induced metabolic disruption in Melissa officinalis by using gas chromatography-mass spectrometry. Analytical and Bioanalytical Chemistry (IF= 4.142) 404 (2), 553-562
38. Sooah Kim, Min Hye Shin, Md Aktar Hossain, Eun Ju Yun, Hojoung Lee, Kyoung Heon Kim* (2011). Metabolite profiling of sucrose effect on the metabolism of Melissa officinalis by gas chromatography-mass spectrometry. Analytical and Bioanalytical Chemistry (IF= 4.142) 399 (10), 3519-3528
39. Sooah Kim, Eun Ju Yun, Jin Seop Bak, Hojoung Lee, Sung Joon Lee, Cheong Tae Kim, Jong-Hoon Lee, Kyoung Heon Kim* (2010). Response surface optimized extraction and chromatographic purification of rosmarinic acid from Melissa officinalis leaves. Food Chemistry (IF= 7.514) 121 (2), 521-526
Pantents Registered
Overseas Patents Registered
1. Kyoung Heon Kim, In-Geol Choi, Eun Ju Yun, Chan Hyoung Lee. Method for improving production yield of monosaccharides in agar by using buffer solution pretreatment. China Patent ZL201580053892.4 (2021. 7. 6)
2. Kyoung Heon Kim, In Geol Choi, Eun Ju Yun, Ah-Reum Lee. Use of 3,6-anhydro- l-galactose for preventing dental caries. China Patent ZL201680060592.3 (2021. 8. 17)
3. Kyoung Heon Kim, In Geol Choi, Nam Joo Kang, Eun Ju Yun, Saeyoung Lee, Ji Hye Kim, Young Ah Kim, Bo Bae Kim, Eun Ji Baek. Method for preparing 3,6-anhydro-l-galactose and use thereof. China Patent ZL201380007372.0 (2020. 7. 3)
4. Kyoung Heon Kim, In Geol Choi, Eun Ju Yun, Jung Hyun Kim. Heat-resistant agarose and monosaccharide production method using same. US Patent 10,655,118 (2020. 5. 19)
5. Kyoung Heon Kim, In Geol Choi, Nam Joo Kang, Eun Ju Yun, Saeyoung Lee, Ji Hye Kim, Young Ah Kim, Bo Bae Kim, Eun Ji Baek. Method for preparing 3,6-anhydro-l-galactose, and use thereof. US Patent 10,639,261 (2020. 5. 5)
6. Kyoung Heon Kim, In-Geol Choi, Chan Hyoung Lee, Hee Taek Kim, Eun Ju Yun. Agarooligosaccharide hydrolase and method for producing 3,6-anhydro-l-galactose and galactose from agarose by using same. China Patent 201480056714.2 (2020. 2. 7)
7. Kyoung Heon Kim, In Geol Choi, Eun Ju Yun, and Ah-Reum Lee. Use of 3,6-anhydro-l-galactose for preventing dental caries. US Patent 10,548,828 (2020. 2. 4)
8. Kyoung Heon Kim, In-Geol Choi, Eun Ju Yun, Saeyoung Lee, Hee Taek Kim. Recombinant microorganism metabolizing 3,6-anhydride-l-galactose and a use thereof. Germany Patent 602014049542.7 (2019. 7. 3)
9. Kyoung Heon Kim, In-Geol Choi, Eun Ju Yun, Saeyoung Lee, Hee Taek Kim. Recombinant microorganism metabolizing 3,6-anhydride-l-galactose and a use thereof. E.P.O Patent 2,995,684 (2019. 7. 3)
10. Kyoung Heon Kim, In Geol Choi, Nam Joo Kang, Eun Ju Yun, Saeyoung Lee, Ji Hye Kim, Young Ah Kim, Bo Bae Kim, Eun Ji Baek. Method for preparing 3,6-anhydro-l-galactose, and use thereof. US Patent 10,071,041 (2018. 9. 11)
11. Kyoung Heon Kim, In-Geol Choi, Chan Hyoung Lee, Hee Taek Kim, Eun Ju Yun. Agarooligosaccharide hydrolase and method for producing 3,6-anhydro-l-galactose and galactose from agarose by using same. France Patent 3,059,309 (2018. 5. 16)
12. Kyoung Heon Kim, In-Geol Choi, Chan Hyoung Lee, Hee Taek Kim, Eun Ju Yun. Agarooligosaccharide hydrolase and method for producing 3,6-anhydro-l-galactose and galactose from agarose by using same. E.P.O Patent 3,059,309 (2018. 5. 16)
13. Kyoung Heon Kim, In-Geol Choi, Chan Hyoung Lee, Hee Taek Kim, Eun Ju Yun. Agarooligosaccharide hydrolase and method for producing 3,6-anhydro-l-galactose and galactose from agarose by using same. US Patent 9,902,983 (2018. 2. 27)
14. Kyoung Heon Kim, In-Geol Choi, Eun Ju Yun, Saeyoung Lee, Hee Taek Kim. Recombinant microorganism metabolizing 3,6-anhydride-l-galactose and a use thereof. US Patent 9,637,761 (2017. 5. 2)
15. Kyoung Heon Kim, In Geol Choi, Nam Joo Kang, Eun Ju Yun, Saeyoung Lee, Ji Hye Kim, Young Ah Kim, Bo Bae Kim, Eun Ji Baek. Method for preparing 3,6-anhydro-l-galactose, and use thereof. Japan Patent 6,022,603 (2016. 10. 14)
16. In Geol Choi, Kyoung Heon Kim, Eun Ju Yun, Saeyoung Lee. Novel 3,6-anhydro-l-galactose dehydrogenase acting on 3,6-anhydro-l-galactose, and production of 3,6-anhydro-l-galctonic acid by using the enzyme. US Patent 9,181,208 (2015. 11. 10)
17. Kyoung Heon Kim, In-Geol Choi, Eun Ju Yun, Saeyoung Lee. Marine bacterium of metabolizing 3,6-anhydro-l-galactose and use of the same. US Patent 8,771,996 (2014. 7. 8)
Korea Patents Registered
1. 김경헌, 진용수, 윤은주, 김인정, 한형민, 유소라. 돌연변이 대장균을 이용한 콜라닉 산 생산. 대한민국특허등록 제10-2254548호 (2021. 5. 14)
2. 김경헌, 진용수, 김동현, 윤은주. 한천으로부터 당 알코올의 생물학적 신규 제조방법. 대한민국특허등록 제10-2193802호 (2020. 12. 16)
3. 김경헌, 진용수, 윤은주, 김동현, 유소라, 조경문, 박나정. 해조류 유래 아가로트리오스의 제조방법 및 프리바이오틱로서의 용도. 대한민국특허등록 제10-2132743호 (2020. 7. 6)
4. 김경헌, 김동현, 윤은주. 홍조류로부터 신규한 당알코올 생산 방법. 대한민국특허등록 제10-2124590호 (2020. 6. 12)
5. 김경헌, 진용수, 윤은주, 김동현, 유소라, 조경문, 박나정. 해조류 유래 아가로트리오스의 제조방법 및 프리바이오틱로서의 용도. 대한민국특허등록 제10-2032799호 (2019. 10. 10)
6. 김경헌, 윤은주, 유소라, 김동현, 이상현, 김정연. 항충치 활성을 갖는 아가로바이오스와 아가로올리고당의 용도. 대한민국특허등록 제10-1960503호 (2019. 3. 14)
7. 김경헌, 진용수, 윤은주, 유소라, 이재원. 다양하고 신규한 퓨코실 올리고당의 제조법 및 그의 용도. 대한민국특허등록 제10-1953375호 (2019. 2. 22)
8. 김경헌, 김동현, 윤은주, 이상현. 해조류 유래 무수갈락토오스의 생산방법. 대한민국특허 등록 제10-1864800호 (2018. 5. 30)
9. 김경헌, 최인걸, 윤은주, 유소라, 조경문. 미생물을 이용한 3,6-안하이드로-L-갈락토오스의 신규한 정제법. 대한민국특허 등록 제10-1851628호 (2018. 4. 18)
10. 김경헌, 윤은주, 김정현, 최인걸. 내열성 한천분해효소 및 이를 이용한 단당류의 생산방법. 대한민국특허 등록 제10-1787331호 (2017. 10. 12)
11. 김경헌, 윤은주, 이아름, 최인걸. 3,6-안하이드로-l-갈락토오스의 항충치 용도. 대한민국특허 등록 제10-1743421호 (2017. 5. 30)
12. 김경헌, 윤은주, 이찬형, 최인걸. 완충용액 전처리를 이용하여 한천에서 단당류의 생산 수율을 개선하는 방법. 대한민국특허 등록 제10-1641173호 (2016. 7. 14)
13. 김경헌, 최인걸, 윤은주, 이세영, 김희택. 3,6-안하이드로-l-갈락토오스를 대사하는 재조합 미생물 및 이의 용도 (원출원). 대한민국특허 등록 제10-1634858호 (2016. 6. 23)
14. 김경헌, 윤은주, 진용수, 김수린. 3-하이드록시부티르산을 생산하는 재조합 미생물 및 이의 용도. 대한민국특허 등록 제10-1605951호 (2016. 3. 17)
15. 김경헌, 최인걸, 강남주, 윤은주, 이세영, 김지혜, 김영아, 김보배, 백은지. 3,6-안하이드로-l-갈락토오스의 제조방법 및 이의 용도 (분할출원). 대한민국특허 등록 제10-1573651호 (2015. 11. 25)
16. 김경헌, 최인걸, 윤은주, 이세영, 김희택. 3,6-안하이드로-l-갈락토오스를 대사하는 재조합 미생물 및 이의 용도 (분할출원). 대한민국특허 등록 제10-1561390호 (2015. 10. 12)
17. 김경헌, 최인걸, 강남주, 윤은주, 이세영, 김지혜, 김영아, 김보배, 백은지. 3,6-안하이드로-l-갈락토오스의 제조방법 및 이의 용도 (원출원). 대한민국특허 등록 제10-1525298호 (2015. 5. 27)
18. 김경헌, 최인걸, 이찬형, 김희택, 윤은주. 신규한 아가로올리고당 분해효소 및 이를 이용한 아가로오스로부터 3,6-안하이드로-l-갈락토오스와 갈락토오스의 생산방법. 대한민국특허 등록 제10-1521711호 (2015. 5. 13)
19. 김경헌, 김희택, 윤은주, Thirumalaisamy Babu. 새로운 아디프산 합성 경로에 의한 아디프산 제조방법. 대한민국특허 등록 제10-1513482호 (2015. 4. 14)
20. 강남주, 김경헌, 최인걸, 김영아, 윤은주, 이세영. 3,6-안하이드로-l-갈락토오스를 포함하는 대장암 예방 또는 치료용 조성물. 대한민국특허 등록 제10-1489732호 (2015. 1. 29)
21. 김경헌, 최인걸, 윤은주, 이세영. 3,6-안하이드로-l-갈락토오스를 대사하는 신규한 해양미생물 및 이 균주의 용도. 대한민국특허 등록 제10-1327248호 (2013. 11. 4)
22. 최인걸, 김경헌, 윤은주, 이세영. 3,6-안하이드로-l-갈락토오스에 작용하는 신규한 3,6-안하이드로-L-갈락토오스 데히드로게나제와 이 효소를 이용한 3,6-안하이드로 갈락토닉산의 생산. 대한민국특허 등록 제10-1316084호 (2013. 10. 1)
23. 김경헌, 최인걸, 윤은주, 신민혜. 사카로파거스 데그러단스 2-40의 조효소를 이용한 3,6-안하이드로-l-갈락토오스와 갈락토오스 생산 및 3,6-안하이드로-L-갈락토오스 정량방법. 대한민국특허 등록 제10-1087265호 (2011. 11. 21)